Molecular pathology as the driving force for personalized oncology

Demystified... Molecular pathology in oncology.

In the past 10 years, molecular biology has found major applications in pathology, particularly in oncology. This has been a field of enormous expansion, where pure science has found a place in clinical practice and is now of everyday use in any academic unit. This demystified review will discuss the techniques used in molecular pathology and then provide examples of how these can be used in on...

What Is The Driving Force Behind Industrial Development In Iran? Rent Seeking And Labor Exploitation As The Driving Force Of Industrial Growth

Pi-dimer formation as the driving force for calix[4]arene-based molecular actuators.

Stable pi-dimers are formed upon oxidation of the model units of proposed calix[4]arene-based molecular actuators in a solvent of low dielectric constant (CH 2Cl 2) at room temperature. Evidence from UV-vis, EPR, and DPV are all in agreement with the pi-dimer formation. In addition, pi-dimer formation is dependent upon the conformational flexibility of the calix[4]arene hinge.

The Impact of Molecular Pathology in Oncology: The Clinician’s Perspective

Since Virchow established the foundation of “Cellular pathology” our understanding of cancer has dramatically and fundamentally changed. We now know that cancer is a complex disease originating from genetic defects and chromosomal alterations in unstable, rapidly dividing cells. As a result normal cellular behavior is gradually lost and the cells acquire a malignant phenotype [5]. These advance...

Driving Force for Nucleation of Multi-Component Gas Hydrate

Based on driving force for crystallization of one-component gas hydrate, in this report an expression for the supersaturation for crystallization of multicomponent gas hydrate is derived. Expressions for the supersaturation are obtained in isothermal and isobaric regimes. The results obtained are applied to the crystallization of hydrates of mixtures of methane plus ethane and can apply to ...